Branched-Chain Amino Acids and Type 2 Diabetes Risk

PLoS Med. 2016 Nov 29;13(11):e1002179. doi: 10.1371/journal.pmed.1002179.

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.

Lotta LA, Scott RA, Sharp SJ, Burgess S, Luan J, Tillin T, Schmidt AF, Imamura F, Stewart ID, Perry JR, Marney L, Koulman A, Karoly ED, Forouhi NG, Sjögren RJ, Näslund E, Zierath JR, Krook A, Savage DB, Griffin JL, Chaturvedi N, Hingorani AD, Khaw KT, Barroso I, McCarthy MI, O’Rahilly S, Wareham NJ, Langenberg C

Direct Link to Paper: http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002179

 

Another step toward universal collaborative methods for metabolomics – Biocrates p180 Kit Ring Trial

Journal:  Analytical Chemistry

Manuscript ID: ac-2016-029307.R1

Title: “Inter-laboratory reproducibility of a targeted metabolomics platform for analysis of human serum and plasma”

Author(s): Siskos, Alexandros; Jain, Pooja ; Römisch-Margl, Werner; Bennett, Mark; Achaintre, David; Asad, Yasmin; Marney, Luke; Richardson, Larissa; Koulman, Albert; Griffin, Julian; Raynaud, Florence; Scalbert, Augustin; Adamski, Jerzy; Prehn, Cornelia; Keun, Hector

Direct Link to Paper: http://pubs.acs.org/doi/pdf/10.1021/acs.analchem.6b02930

2015 – Diabetes, genetics, and the roll of lipid metabolism: pushing our ability to conduct system’s biology investigations with huge sample sizes and cutting edge analytical chemistry

Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes.

Eiden M, Koulman A, Hatunic M, West JA, Murfitt S, Osei M, Adams C, Wang X, Chu Y, Marney L, Roberts LD, O’Rahilly S, Semple RK, Savage DB, Griffin JL.

Genome Med. 2015 Jun 28;7:63. doi: 10.1186/s13073-015-0179-6. eCollection 2015.

PMID:
26273324

Free PMC Article